A team of doctors and researchers from IRCCS San Raffaele Hospital in Milan, Vita-Salute San Raffaele University (UniSR), and Sant'Anna School of Advanced Studies in Pisa has achieved promising results in the treatment of spinal cord injuries using an innovative high-frequency epidural electrical stimulation protocol. The study, which was published in the journal Science Translational Medicine, demonstrated that this technique substantially reduces muscle spasticity and enhances motor skills in patients with incomplete spinal cord injuries. In 2023, the first two patients treated with the spinal cord neurostimulator, a device currently in use for pain therapy, exhibited improvement in motor function. High-frequency stimulation paired with rehabilitation resulted in considerable gains in muscle strength, locomotion, and motor function. In addition, the program reduced abnormal reflexes and involuntary muscular contractions, resulting in more fluid and natural motions.